The in Vitro Formation of an Oxidizing Agent by Surviving Tissues and Sulfanilamide.
نویسنده
چکیده
Methemoglobin formation generally occurs during sulfanilamide therapy in humans (1, 2, 3, 4, 5). From the clinical statistics on methemoglobinemia it has been deduced that sulfanilamide is partially converted by the body into some active agent which can function as an oxidant (5). It is the purpose of this paper to determine whether the oxidation of hemoglobin is performed by sulfanilamide itself or whether the active agent is produced through the interaction of tissues and sulfanilamide.
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 18 5 شماره
صفحات -
تاریخ انتشار 1939